2-alpha-Methyl-dopaminimino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalène, ses sels, et procédé pour sa préparation

2-alpha-Methyl-dopaminimino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene, its salts, and a process for preparation thereof

2-alpha-Methyl-dopaminimino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalin, seine Salze, und Verfahren zu dessen Herstellung


Derivatives of 2-amino-6,7-dihydroxytetrahydronaph- thalene (ADTN) represented by the formula wherein R is OH, alkyloxy, hydroxyalkyl or acyloxy, and R' is an aryl alkyl in which the aryl group is benzyl, substituted benzyl, phenyl or substituted phenyl and the alkyl group is a straight or branched chain alkyl having one to twenty carbon atoms, and the pharmaceutically acceptable salts thereof. These derivatives of 2-amino-6,7-dihydroxytetrahydro- naphthalene are useful as inotropes. The compounds may be prepared by reductive amination of the protected 2-amino-6,7-dihydroxytetrahydro- naphthalene.




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NO-Patent Citations (2)

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